Trichloroacetyl isocyanate → HCID 13047563, compound

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([OH:14])[C:6](=[C:10]([O:12][CH3:13])[CH:11]=1)[CH:7]=[N:8]O.ClC(Cl)(Cl)C(N=C=O)=O>>[CH3:13][O:12][C:10]1[C:6]2[CH:7]=[N:8][O:14][C:5]=2[CH:4]=[C:3]([O:2][CH3:1])[CH:11]=1

Participants

Reactant 2

HCID 76400Trichloroacetyl isocyanate

HCID 357307HCID 357307, compound

Product 1

HCID 13047563HCID 13047563, compoundYield 72.6%

Procedure

Following the procedure substantially the same as described in Example 1, Step C, 1.97 g of 4,6-dimethoxysalicylaldoxime is treated with 2.0 g of trichloroacetylisocyanate to yield 1.3 g (72.6%) of 4,6-dimethoxy-1,2-benzisoxazole, m.p. 100°-101° C.

Sources & evidence

ORD record: ord-5fbe7a9b7aa6473ea5fb7b701ba14e20
Source dataset: uspto-grants-1979_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04156005

Reaction notes

Loading…