HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 263134Generated: October 25, 2026
Water → 5-[2,6,6-trimethyl-3-oxo-4(S)-(phenoxyacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al
https://huagongshe.com/reaction/263134
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Phenoxyacetyl chloride | HCID 69703 | — |
| Reactant | Rac. 5-(2,6,6-trimethyl-3-oxo-4-hydroxy-cyclohex-1-en-1-yl)-3-methyl-penta-2,4-dien-1-al | HCID 73769876 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 5-[2,6,6-trimethyl-3-oxo-4(S)-(phenoxyacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al | HCID 53795135 | — |
Reaction Steps
14 g of the hydroxyketoaldehyde of formula XIII obtained in Example 26 are dissolved in 200 ml of diethyl ether. 20 ml of pyridine are added to the solution at 0° C. and 12 g of phenoxyacetic acid chloride are then added dropwise. The mixture is stirred for 2 hours at 0° C. and then poured into water and extracted with diethyl ether. The 5-[2,6,6-trimethyl-3-oxo-4(S)-(phenoxyacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al (IIA) is isolated from the ether extract.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04156090 |
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| Source dataset | uspto-grants-1979_05 |
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| ORD ID | ord-afd8878daa1a4d32ae01c955d8fed9e6 |
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| Source note | uspto-grants-1979_05 |
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