Nonanoyl chloride → 4-(S)-Isopropyl-3-(1-oxononyl)-2-oxazolidinone

HRID 263448Notes

Reaction equation

HRID 263448 reaction equation
[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[NH:5]1)([CH3:3])[CH3:2].[C:10](Cl)(=[O:19])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>>[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[N:5]1[C:10](=[O:19])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 69819Nonanoyl chlorideHCID 7157133(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one

Product 1

HCID 105880604-(S)-Isopropyl-3-(1-oxononyl)-2-oxazolidinoneYield 97.2%

Procedure

Following the procedure described in Referential Example 3, but using 4-(S)-isopropyl-2-oxazolidinone (4.99 g) and nonanoyl chloride (7.16 g), the desired compound (10.12 g) was obtained.

Sources & evidence

ORD record
ord-ca72507f5c1b4a7d9f6f2c580aada948
Source dataset
uspto-grants-1997_07
Patent number
US05643908

Reaction notes

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