Sodium Methoxide → 3-methoxy-11-methylene-11H-s-triazolo[3,4-b][3]benzazepine

HRID 26534

Reaction equation

[CH2:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH:6]=[CH:5][N:4]2[C:13](S(C)=O)=[N:14][N:15]=[C:3]12.[CH3:19][O-:20].[Na+]>>[CH3:19][O:20][C:13]1[N:4]2[C:3]([C:2](=[CH2:1])[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=3[CH:6]=[CH:5]2)=[N:15][N:14]=1

Participants

Reactant 2

HCID 10942334Sodium Methoxide

HCID 2132336711-methylene-3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine

Product 1

HCID 213233353-methoxy-11-methylene-11H-s-triazolo[3,4-b][3]benzazepine

Procedure

The reaction of 11-methylene-3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine with sodium methoxide yielded 3-methoxy-11-methylene-11H-s-triazolo[3,4-b][3]benzazepine. Colorless needles (as recrystallized from ethyl acetate), melting point: 160°-161° C.

Sources & evidence

ORD record: ord-9fe685a61e1441ed99838e6823645101
Source dataset: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04150139

Linked notes

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