Sodium Methoxide → 3-methoxy-11H-s-triazolo[3,4-b][3]benzazepin-11-one

Reaction equation

CS([C:4]1[N:13]2[C:7]([C:8](=[O:18])[C:9]3[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=3[CH:11]=[CH:12]2)=[N:6][N:5]=1)=O.[CH3:19][O-:20].[Na+]>>[CH3:19][O:20][C:4]1[N:13]2[C:7]([C:8](=[O:18])[C:9]3[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=3[CH:11]=[CH:12]2)=[N:6][N:5]=1

Participants

Reactant 2

HCID 10942334Sodium Methoxide

HCID 213233503-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepin-11-one

Product 1

HCID 213234423-methoxy-11H-s-triazolo[3,4-b][3]benzazepin-11-one

Procedure

The reaction of 3-methylsulfinyl-11H-s-triazolo [3,4-b][3]benzazepin-11-one with sodium methoxide yielded 3-methoxy-11H-s-triazolo[3,4-b][3]benzazepin-11-one. Colorless platelets (as recrystallized from methanol), melting point: 149°-150° C.

Sources & evidence

ORD record: ord-6446d98e9a4b489db180f49e76b5d11d
Source dataset: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04150139

Reaction notes

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