Carbon Disulfide → (2-{[(5-Methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)carbamodithioic acid

HRID 26721

Reaction equation

HRID 26721 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[CH2:7][S:8][CH2:9][CH2:10][NH2:11].[C:12](=[S:14])=[S:13]>C(O)C>[CH3:1][C:2]1[NH:3][CH:4]=[N:5][C:6]=1[CH2:7][S:8][CH2:9][CH2:10][NH:11][C:12](=[S:13])[SH:14]

Participants

4

Reactant 2

HCID 6348Carbon DisulfideHCID 178433288HCID 178433288, compound

Product 1

HCID 15566013(2-{[(5-Methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)carbamodithioic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 4-methyl-5-((2-aminoethyl)thiomethyl)imidazole (10.2 g) in ethanol (75 ml) was added slowly, with stirring, to carbon disulphide (200 ml). The mixture was set aside overnight at room temperature and the solid formed was collected and recrystallised from aqueous isopropyl alcohol to afford N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]dithiocarbamic acid (9.8 g)., m.p. 127°-129°.

Workup

  1. customthe solid formed
  2. customwas collected
  3. customrecrystallised from aqueous isopropyl alcohol

Sources & evidence

ORD record
ord-e43ba620e5dc42b7952b3bc7829c8aa1
Source dataset
uspto-grants-1979_04
Patent number
US04151289

Linked notes

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