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Potassium Hydroxide → 2-[(2-Chlorophenyl)methyl]aniline

HRID 267411
Notes
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Reaction equation

HRID 267411 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[C:4](=NN)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11].[OH-].[K+]>C(O)COCCO>[Cl:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[CH2:4][C:3]1[CH:14]=[CH:15][CH:16]=[CH:17][C:2]=1[NH2:1]
ParticipantsProcedureSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 867330942-Amino-2'-chlorobenzophenone hydrazone

Product 1

HCID 134266642-[(2-Chlorophenyl)methyl]aniline

Reagents, catalysts & solvents 1

HCID 8117Diethylene GlycolSolvent

Procedure

In the manner given in Preparation 11, 2-amino-2'-chlorobenzophenone hydrazone is refluxed with potassium hydroxide in diethylene glycol to give 2-(o-chlorobenzyl)aniline.

Sources & evidence

ORD record
ord-62515786ec084efda5f8b229643a7a79
Source dataset
uspto-grants-1976_03
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US03941803

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes