m-Anisoyl chloride → 3-(3-Methoxybenzoyl)-2-phenylbenzofuran

Reaction equation

[C:1]1([C:7]2[O:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:16](Cl)(=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[CH:18]=1>>[CH3:24][O:23][C:19]1[CH:18]=[C:17]([CH:22]=[CH:21][CH:20]=1)[C:16]([C:11]1[C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[O:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:25]

Participants

Reactant 2

HCID 74374m-Anisoyl chloride

HCID 35179362-Phenyl-benzofuran

Product 1

HCID 214353383-(3-Methoxybenzoyl)-2-phenylbenzofuran

Procedure

Acylation of 10.5 g. (0.054 mol.) of 2-phenylbenzofuran with 9.9 g. (0.058 mol.) of m-anisoyl chloride according to the procedure described in Example 1 gives 3-(3-methoxybenzoyl)-2-phenylbenzofuran.

Sources & evidence

ORD record: ord-859c077cf72f4f7fb433c1394290e659
Source dataset: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03947470

Reaction notes

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