Benzenamine, N-sulfinyl- → N-sulfinyl-N-'-(3-trifluoromethylphenyl)-hydrazine

HRID 268438

Reaction equation

HRID 268438 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:4]=[C:5]([NH:9][NH2:10])[CH:6]=[CH:7][CH:8]=1.[S:13](=NC1C=CC=CC=1)=[O:14]>CO.C(O)(=O)C>[S:13](=[N:10][NH:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:11])([F:12])[F:1])[CH:4]=1)=[O:14]

Participants

5

Reactant 2

HCID 70739Benzenamine, N-sulfinyl-HCID 98650(3-(Trifluoromethyl)phenyl)hydrazine

Product 1

HCID 21552090N-sulfinyl-N-'-(3-trifluoromethylphenyl)-hydrazineYield 64%

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 887MethanolSolvent

Procedure

20 g (0.113 mole) of 3-trifluoromethyl-phenylhydrazine were dissolved in 50 ml of methanol with addition of 5 ml of acetic acid; 16 g (0.115 mole) of sulfinylaniline were added dropwise at a temperature of 22°C. The product crystallized out while the temperature rose to about 30°C. After filtration and drying, 16 g of N-sulfinyl-N-' -(3-trifluoromethylphenyl)-hydrazine of melting point 100°C were obtained. The yield was 64% of theory.

Workup

  1. customThe product crystallized out while the temperature
  2. customrose to about 30°C
  3. filtrationAfter filtration
  4. customdrying

Sources & evidence

ORD record
ord-e391a39ac46b42f3ad518b84f023b3fd
Source dataset
uspto-grants-1976_03
Patent number
US03947513

Linked notes

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