3-(3-cyano-1H-Indol-4-yl)-3-phenyl-propionic acid ethyl ester → 3-(5-Methoxy-1H-indol-6-yl)-3-phenyl-propionic acid ethyl ester
Reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH:5]=[C:6]([C:13]1[CH:21]=[C:20]2[C:16]([CH:17]=[CH:18][NH:19]2)=[CH:15][C:14]=1[O:22][CH3:23])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2].C(OC(=O)CC(C1C=CC=C2C=1C(C#N)=CN2)C1C=CC=CC=1)C>>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH:6]([C:13]1[CH:21]=[C:20]2[C:16]([CH:17]=[CH:18][NH:19]2)=[CH:15][C:14]=1[O:22][CH3:23])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]Participants
3
Procedure
3-(5-Methoxy-1H-indol-6-yl)-3-phenyl-propionic acid ethyl ester CXXXIV was prepared from 3-(5-methoxy-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described above for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-propionic acid ethyl ester LIX (Example 14)
Sources & evidence
- ORD record
- ord-19ed6895b39c4ea38585eb14d1da4600
- Source dataset