Acetic Anhydride → HCID 86736488, compound

Reaction equation

[Br:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15](O)(C)[CH2:16][C:17](O)=O.[C:22]([O:25]C(=O)C)(=[O:24])C>>[Br:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH:16]=[CH:17][C:22]([OH:25])=[O:24]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 213225673-(2',4'-Dibromobiphenylyl)-3-hydroxybutyric acid

Product 1

HCID 86736488HCID 86736488, compound

Procedure

1 g. of 3-(2',4'-dibromobiphenylyl)-3-hydroxybutyric acid and 10 ml. of acetic anhydride are heated under reflux for 2 hours and the mixture is poured onto ice and worked up in the customary manner to give 3-(2',4'-dibromo-4-biphenylyl-2-butenoic acid.

Workup

temperatureunder reflux for 2 hours
additionthe mixture is poured onto ice

Sources & evidence

ORD record: ord-edcb1023a5214e3eb85b16d8b4b1cb68
Source dataset: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04151302

Reaction notes

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