HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 1-Hexanol | HCID 8103 | — |
| Reactant | 3-(2',4'-Difluoro-4-biphenylyl)butyronitrile | HCID 21322521 | — |
| Product | 3-(2',4'-Difluoro-4-biphenylyl)butyric acid | HCID 21322540 | — |
Reaction Steps
1 g. of 3-(2',4'-difluoro-4-biphenylyl)butyronitrile, 3 ml. of n-hexanol and 0.1 g. of concentrated H2SO4 are heated under reflux for 48 hours. 3 ml. of water are added and the mixture is heated under reflux for 48 hours more and worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)-butyric acid, m.p. 109°-110°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151302 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-ac0eb0931272464d9cce0fa5ac820a65 |
| Source note | uspto-grants-1979_04 |