HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-Bromo-5-chlorobenzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Bromo-5-chlorobenzoic acid | HCID 89027 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 2-Bromo-5-chlorobenzoic acid ethyl ester | HCID 69309566 | — |
Reaction Steps
A solution of 2-bromo-5-chlorobenzoic acid in ethanol (10 ml) and sulphuric acid (0.5 ml) was refluxed for 20 hours then cooled and evaporated. The residue was dissolved in diethyl ether/water and the organic layer dried (magnesium sulphate) and evaporated to give 516 mg of light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446222B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-53864e97ac024a7b8db7f1a8a5c79c24 |
| Source note | uspto-grants-2008_11 |