HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ticlopidine → 4,5,6,7-Tetrahydrothieno(3,2-c)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ticlopidine | HCID 5472 | — |
| Reactant | Thiopheneethanamine | HCID 116521 | — |
| Product | 4,5,6,7-Tetrahydrothieno(3,2-c)pyridine | HCID 3085076 | — |
Reaction Steps
Alternatively, ticlopidine of formula (1a) may also be synthesized by directly cyclizing 2-(2-aminoethyl)thiophene of formula (a) with a formylating agent to obtain 4,5,6,7-tetrahydrothieno[3,2-c]pyridine of formula (f), and then reacting the compound (f) with a compound of formula (b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449580B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-8918957f0be54d69b3276552a895d2b6 |
| Source note | uspto-grants-2008_11 |