1-Cyano-2-ethoxy-2-methylaminoethylene → HCID 178483853, compound
Reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[CH2:7][S:8][CH2:9][CH2:10][NH2:11].[C:12]([CH:14]=[C:15](OCC)[NH:16][CH3:17])#[N:13]>N1C=CC=CC=1>[C:12]([CH:14]=[C:15]([NH:16][CH3:17])[NH:11][CH2:10][CH2:9][S:8][CH2:7][C:6]1[NH:5][CH:4]=[N:3][C:2]=1[CH3:1])#[N:13]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole (3.5 g) was added to a solution of 1-cyano-2-ethoxy-2-methylaminoethylene in pyridine (3.1 g) and the solution was stirred for 5 hours at 100°. The product was chromatographed on a column of neutral alumina with elution by chloroform/ethyl acetate (1:1) to give the title compound as a glass.
Workup
- customThe product was chromatographed on a column of neutral alumina with elution by chloroform/ethyl acetate (1:1)
Sources & evidence
- ORD record
- ord-10944535e2734a209418e4008f02eba6
- Source dataset
- uspto-grants-1980_09
- Patent number
- US04220652
Reaction notes
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