Thionyl Chloride → 3-Chloro-5-(chloromethyl)pyridine hydrochloride
Reaction equation
O[CH2:2][C:3]1[CH:4]=[C:5]([Cl:9])[CH:6]=[N:7][CH:8]=1.S(Cl)([Cl:12])=O>>[ClH:9].[Cl:9][C:5]1[CH:6]=[N:7][CH:8]=[C:3]([CH2:2][Cl:12])[CH:4]=1Participants
3
Procedure
The title compound was prepared in accordance with the general method of example E from 5-(hydroxymethyl)-3-chloropyridine and thionylchloride.
Sources & evidence
- ORD record
- ord-5695360097d74a099ce2511de3f73db8
- Source dataset
- uspto-grants-2008_11
- Patent number
- US07452909B2
Reaction notes
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