HuagongsheHuagongshe Chemistry Print Report · For research reference only
Valproic Acid → (-)-Carnitine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Valproic Acid | HCID 3121 | — |
| Reactant | (-)-Carnitine | HCID 10917 | — |
| Reactant | L-carnitine magnesium valproate | HCID 86623374 | — |
| Solvent | Water | HCID 962 | — |
| Product | (-)-Carnitine | HCID 10917 | — |
| Product | Valproate | HCID 3549980 | — |
| Product | Magnesium | HCID 5462224 | — |
Reaction Steps
As we discovered and disclose in Example 2, L-carnitine magnesium valproate, another embodiment of the present invention, is a white solid having a melting point of 77.2° C., different from the melting point of L-carnitine. The 1H-NMR spectrum of L-carnitine magnesium valproate (FIG. 3) differs from that of the starting materials (i.e., L-carnitine and valproic acid) and confirms the structure. L-carnitine magnesium valproate is nearly odorless and free from objectionable taste. L-Carnitine magnesium valproate is soluble in water, and aqueous solutions of this salt provide bioavailable L-carnitine, magnesium, and valproate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456216B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-03713faf71dc4e8fa2470049d9690cb2 |
| Source note | uspto-grants-2008_11 |