5-Hydroxy-4,4-dimethyl-1-pentanesulfonamide → 1-Pentanesulfonamide, 4,4-dimethyl-5-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

HRID 274271

Reaction equation

HRID 274271 reaction equation
[OH:1][CH2:2][C:3]([CH3:12])([CH3:11])[CH2:4][CH2:5][CH2:6][S:7]([NH2:10])(=[O:9])=[O:8].Cl[C:14]1[C:15]([CH3:23])=[CH:16][C:17]2[N:18]([N:20]=[CH:21][N:22]=2)[N:19]=1>>[CH3:11][C:3]([CH3:12])([CH2:4][CH2:5][CH2:6][S:7](=[O:8])(=[O:9])[NH2:10])[CH2:2][O:1][C:14]1[C:15]([CH3:23])=[CH:16][C:17]2[N:18]([N:20]=[CH:21][N:22]=2)[N:19]=1

Participants

3

Reactant 2

HCID 107265205-Hydroxy-4,4-dimethyl-1-pentanesulfonamideHCID 118051586-Chloro-7-methyl-[1,2,4]triazolo[1,5-b]pyridazine

Product 1

HCID 30737881-Pentanesulfonamide, 4,4-dimethyl-5-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

Procedure

Using 5-hydroxy-4,4-dimethyl-1-pentanesulfonamide and 6-chloro-7-methyl[1,2,4]triazolo[1,5-b]pyridazine, the same reaction was conducted as in Example 5 to produce the title compound. m.p. 171°-172° C.

Workup

  1. customthe same reaction

Sources & evidence

ORD record
ord-55d85fa45f36489eabca2860c9c974a7
Source dataset
uspto-grants-1995_02
Patent number
US05389633

Linked notes

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