2-Methylbenzothiazole → HCID 22930888, compound

HRID 275251

Reaction equation

HRID 275251 reaction equation
[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[Br:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18]>>[Br-:11].[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N+:6]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18]

Participants

3

Reactant 2

HCID 84462-MethylbenzothiazoleHCID 202106-Bromohexanoic acid

Product 1

HCID 22930888HCID 22930888, compoundYield 212.9%

Conditions

Temperature
120 °C

Procedure

2-methyl benzothiazole (19.5g, 0.1M) and 6-bromohexanoic acid (15.3g, 0.1M) were mixed and heated at 120° C. for 4 hours under continuous agitation. The resulting solid was broken up, ground with ether and then filtered. The filtrate was washed with more ether (250ml) to yield an off-white powder (57.5g).

Workup

  1. filtrationground with ether and then filtered
  2. washThe filtrate was washed with more ether (250ml)

Sources & evidence

ORD record
ord-e9b9ffc8121942548db3ebc77f1545c8
Source dataset
uspto-grants-1995_02
Patent number
US05393654

Linked notes

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