Ethylene Glycol → Methyl 2-methyl-1,3-dioxolane-2-butanoate

HRID 275303

Reaction equation

[O:1]=[C:2]([CH3:10])[CH2:3][CH2:4][CH2:5][C:6]([O:8][CH3:9])=[O:7].[CH2:11](O)[CH2:12][OH:13]>>[CH3:10][C:2]1([CH2:3][CH2:4][CH2:5][C:6]([O:8][CH3:9])=[O:7])[O:13][CH2:12][CH2:11][O:1]1

Participants

Reactant 2

HCID 174Ethylene Glycol

HCID 84129Methyl 5-oxohexanoate

Product 1

HCID 3310317Methyl 2-methyl-1,3-dioxolane-2-butanoate

Procedure

Methyl 2-methyl-1,3-dioxolane-2-butanoate (25) was prepared from methyl 5-oxohexanoate and ethylene glycol in the manner described in Example 17 above on a 28 mmol scale to yield 4.94 g (94%) of product. The product was employed immediately in the manner described in Example 26 below.

Sources & evidence

ORD record: ord-ba8293fb5240431eb4f2b315ab18fc2c
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05393747

Linked notes

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