4-sulfamoylthiobenzamide → HCID 9864691, compound

HRID 275665

Reaction equation

HRID 275665 reaction equation
Br[CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:11])[CH:8]=2)[C:3]1=[O:12].[S:13]([C:17]1[CH:25]=[CH:24][C:20]([C:21]([NH2:23])=[S:22])=[CH:19][CH:18]=1)(=[O:16])(=[O:15])[NH2:14]>>[Cl:11][C:7]1[CH:6]=[CH:5][C:4]2[C:3]3([OH:12])[N:23]=[C:21]([C:20]4[CH:19]=[CH:18][C:17]([S:13]([NH2:14])(=[O:15])=[O:16])=[CH:25][CH:24]=4)[S:22][CH:2]3[CH2:10][C:9]=2[CH:8]=1

Participants

3

Reactant 2

HCID 30032664-sulfamoylthiobenzamideHCID 113340692-Bromo-5-chloro-2,3-dihydro-1H-inden-1-one

Product 1

HCID 9864691HCID 9864691, compound

Procedure

4-(6-Chloro-3a-hydroxy-8,8a-dihydro-3aH-indeno[1,2-d]thiazol-2-yl)benzenesulfonamide is prepared in a similar manner by reacting 2-bromo-5-chloroindan-1-one with 4-sulfamoylthiobenzamide. The compound has a melting point of 160° C.

Sources & evidence

ORD record
ord-e5b29e27975f438baf5df7248b349d71
Source dataset
uspto-grants-2002_03
Patent number
US06352987B2

Linked notes

Loading…