3,4,5-Trimethoxybenzyl alcohol → 3,4,5-Trimethoxybenzaldehyde

HRID 27847

Reaction equation

HRID 27847 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:13][CH3:14])[C:10]=1[O:11][CH3:12])[CH2:6][OH:7]>CC(C)=O>[CH3:14][O:13][C:9]1[CH:8]=[C:5]([CH:4]=[C:3]([O:2][CH3:1])[C:10]=1[O:11][CH3:12])[CH:6]=[O:7]

Participants

3

Reactant 1

HCID 774493,4,5-Trimethoxybenzyl alcohol

Product 1

HCID 68583,4,5-TrimethoxybenzaldehydeYield 76%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Using a similar method to Example 1, a mixture of 400 parts of 3,4,5-trimethoxybenzyl alcohol and 400 parts of acetone with 380 parts of air is passed per hour over the catalyst at 530° C. and 1.2 bar. The residence time is 0.04 second and the throughput is 0.57 tonne/m2.h. 302 parts of 3,4,5-trimethoxybenzaldehyde (in the form of a 44 percent strength by weight solution) are obtained per hour, corresponding to a yield of 76% of theory. The conversion is 95 percent and the space-time yield is 14 grams of 3,4,5-trimethoxybenzaldehyde per cm3 of catalyst volume per hour.

Workup

  1. waitis passed per hour over the catalyst at 530° C.

Sources & evidence

ORD record
ord-4638ca2829914dca8f8e4810ade3c8fb
Source dataset
uspto-grants-1980_09
Patent number
US04224254

Linked notes

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