3-Iodotoluene → Methyl 4-(3-methylphenyl)-2-oxobutyrate

HRID 278474

Reaction equation

I[C:2]1[CH:3]=[C:4]([CH3:8])[CH:5]=[CH:6][CH:7]=1.[OH:9][CH:10]([CH:15]=[CH2:16])[C:11]([O:13][CH3:14])=[O:12]>>[CH3:8][C:4]1[CH:3]=[C:2]([CH2:16][CH2:15][C:10](=[O:9])[C:11]([O:13][CH3:14])=[O:12])[CH:7]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 122683-Iodotoluene

HCID 545123Methyl 2-hydroxybut-3-enoate

Product 1

HCID 22628528Methyl 4-(3-methylphenyl)-2-oxobutyrate

Procedure

Methyl 4-(3-methylphenyl)-2-oxobutyrate was prepared as a pale yellow oil from 3-iodotoluene and methyl 2-hydroxy-3-butenoate.

Sources & evidence

ORD record: ord-bb4dbc8bb61d48228e5987fcd32da98a
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06359145B1

Linked notes

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