3,5,5-Trimethylhexanoic acid → n-(3,5,5-Trimethylhexanoyl)-2-octyldodecylamine

HRID 278533

Reaction equation

HRID 278533 reaction equation
[CH3:1][CH:2]([CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])[CH2:3][C:4]([OH:6])=O.[CH2:12]([CH:20]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:21][NH2:22])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>CCCCCCC>[CH3:1][CH:2]([CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])[CH2:3][C:4]([NH:22][CH2:21][CH:20]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[O:6]

Participants

4

Reactant 2

HCID 909603,5,5-Trimethylhexanoic acidHCID 187619992-n-Octyl-1-dodecylamine

Product 1

HCID 18673283n-(3,5,5-Trimethylhexanoyl)-2-octyldodecylamine

Reagents, catalysts & solvents 1

HCID 8900HeptaneSolvent

Procedure

3.6 g of 3,5,5-trimethylhexanoic acid and 6.8 g. of 2-octyldodecylamine were mixed together in the tube of a microwave machine (Maxidigest™ MX 350 from the company Prolabo; frequency 2450±50 MHz, modulable power 300 W). After irradiation for about 50 minutes at 170° C.±10° C., the reaction mixture was dissolved in heptane and then purified on silica. 7 g of the desired amide were obtained.

Workup

  1. customAfter irradiation for about 50 minutes at 170° C.±10° C.
  2. custompurified on silica

Sources & evidence

ORD record
ord-0f09de70df754ed39b82a2c0ae0c94c3
Source dataset
uspto-grants-2002_03
Patent number
US06359175B1

Linked notes

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