3-Bromo-1-indanone → 1H-inden-1-one

HRID 279153

Reaction equation

HRID 279153 reaction equation
Br[CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH2:3]1>C(OCC)C>[C:4]1(=[O:11])[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:2]=[CH:3]1

Participants

3

Reactant 1

HCID 117459123-Bromo-1-indanone

Product 1

HCID 118153841H-inden-1-one

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

3-Bromoindan-1-one (1.5) was dissolved in diethyl ether (10 ml). The temperature was kept at +2-+4 while TEA (2.7 ml) was added. The resulting mixture was further stirred at +2-+4 for 2 hours. The precipitated salt was filtered off and the filtrate evaporated. The crude inden-1-one was used for further reaction without purification. Yield was 0.9 g.

Workup

  1. additionwas added
  2. filtrationThe precipitated salt was filtered off
  3. customthe filtrate evaporated
  4. customThe crude inden-1-one was used for further reaction without purification

Sources & evidence

ORD record
ord-099caa22924f4e3cb6b0fef9973b9406
Source dataset
uspto-grants-2002_03
Patent number
US06362211B1

Linked notes

Loading…