HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylglyoxal → N-(2-(4-Methylphenyl)ethyl)-2-hydroxy-2-phenylethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylglyoxal | HCID 14090 | — |
| Reactant | p-Methylphenethylamine | HCID 76751 | — |
| Reactant | 3-(Trifluoromethyl)phenylglyoxal | HCID 2783284 | — |
| Product | N-(2-(4-Methylphenyl)ethyl)-2-hydroxy-2-phenylethanamine | HCID 23322154 | — |
Reaction Steps
The title compound was prepared in the manner described in Example 9, replacing 2-(4-methylphenyl)-1,1-dimethylethanamine by 2-(4-methylphenyl)ethanamine and 3-trifluoromethylphenylglyoxal by phenylglyoxal. The chromatographed material was recrystallised from hexane to give the title compound, mp 95°-97°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588749 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-2b3502e5393e4644bdebfb3df05b7ba9 |
| Source note | uspto-grants-1986_05 |