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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28064Generated: October 24, 2026

Glutaric anhydride → Theophylline

https://huagongshe.com/en/reaction/28064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlutaric anhydrideHCID 7940—
Reactant5,6-Diamino-1,3-dimethyluracilHCID 79501—
ProductTheophyllineHCID 2153—

Reaction Steps

Following the method of Cook et al, Res. Comm. Chem. Path. Pharm. 13:497(1976), 4,5-diamino-1,3-dimethylpyrimidine-2,6-dione is heated with glutaric anhydride to yield the following: ##STR12##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04225485
Source datasetuspto-grants-1980_09
ORD IDord-a11fefbd31c743d89293b71722a413e5
Source noteuspto-grants-1980_09