Isoquinolin-3-Amine → 3-(1,4-Diazacycloheptan-1-yl)-isoquinoline

HRID 280689

Reaction equation

HRID 280689 reaction equation
[NH2:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.Cl[CH2:13][CH2:14][NH:15][CH2:16][CH2:17][CH2:18]Cl>>[N:1]1([C:2]2[N:3]=[CH:4][C:5]3[C:10]([CH:11]=2)=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:18][CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 311869Isoquinolin-3-AmineHCID 30605423-chloro-N-(2-chloroethyl)propan-1-amine

Product 1

HCID 130255903-(1,4-Diazacycloheptan-1-yl)-isoquinoline

Procedure

3-(1,4-Diazacycloheptan-1-yl)-isoquinoline is prepared from 3-aminoisoquinoline and 2-chloroethyl-3-chloropropylamine.

Sources & evidence

ORD record
ord-087f7cfaa6a24c5689eed7d46aba8008
Source dataset
uspto-grants-1986_05
Patent number
US04590273

Linked notes

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