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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280723Generated: October 27, 2026

M-Cresol → 2,4,6-Trimethylphenol

https://huagongshe.com/reaction/280723

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
ReactantP-CresolHCID 2879—
ReactantDimethyl EtherHCID 8254—
Reactant2,3,6-TrimethylphenolHCID 17016—
SolventMethanolHCID 887—
Product2,4,6-TrimethylphenolHCID 10698—

Reaction Steps

methylating meta-cresol and para-cresol in the ortho position by reacting the meta-cresol and para-cresol with methanol, dimethyl ether or a mixture thereof at a temperature of 270° to 450° C., at a pressure of atmospheric to 100 bar and in the presence of a catalyst bed without a residence time of 0.01 to 10 seconds, whereby a mixture of 2,3,6-trimethylphenol and 2,4,6-trimethylphenol is produced;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04590306
Source datasetuspto-grants-1986_05
ORD IDord-1fec35ca492647bfab2337bac42a837c
Source noteuspto-grants-1986_05