Acetone → 2,3-Dimethyl-8-(2,6-dimethylbenzyloxy)imidazo[1,2-a]pyridine

HRID 281077

Reaction equation

HRID 281077 reaction equation
[CH2:31]([Cl:32])[Cl:33].[CH3:13][c:14]1[c:15]([CH2:16][Cl:17])[c:18]([CH3:22])[cH:19][cH:20][cH:21]1.[CH3:34][C:35](=[O:36])[CH3:37].[I-:24].[Na+:23].[Na+:25].[Na+:26].[O-:27][C:28](=[O:29])[O-:30].[OH:1][c:2]1[c:3]2[n:4]([cH:5][cH:6][cH:7]1)[c:8]([CH3:12])[c:9]([CH3:11])[n:10]2>>[O:1]([c:2]1[c:3]2[n:4]([cH:5][cH:6][cH:7]1)[c:8]([CH3:12])[c:9]([CH3:11])[n:10]2)[CH2:16][c:15]1[c:14]([CH3:13])[cH:21][cH:20][cH:19][c:18]1[CH3:22]

Participants

8

Reactant 7

HCID 180AcetoneHCID 923Sodium ion3×HCID 6344DichloromethaneHCID 19660Carbonate IonHCID 30165Iodide IonHCID 2211542,6-Dimethylbenzyl ChlorideHCID 224679492,3-Dimethylimidazo[1,2-a]pyridin-8-ol

Product 1

HCID 217173362,3-Dimethyl-8-(2,6-dimethylbenzyloxy)imidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-6a3018e9ffcf4e8e85ae92017e553a53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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