4-(3-((2-(1-Hydroxycyclohexyl)ethyl)-4-oxo-2-thiazolidinyl)propyl)benzoic acid → Ethyl 4-{3-[3-[2-(1-Hydroxycyclohexyl)ethyl]-4-oxo-2-thiazolidinyl]propyl}-3-chlorobenzoate

HRID 28212

Reaction equation

HRID 28212 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][C:12]=1[CH2:13][CH2:14][CH2:15][CH:16]=O)[C:5]([O:7][CH2:8][CH3:9])=[O:6].[OH:18][C:19]1([CH2:25][CH2:26][N:27]2[C:31](=[O:32])[CH2:30][S:29]C2CCCC2C=CC(C(O)=O)=CC=2)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[OH:18][C:19]1([CH2:25][CH2:26][N:27]2[C:31](=[O:32])[CH2:30][S:29][CH:16]2[CH2:15][CH2:14][CH2:13][C:12]2[CH:11]=[CH:10][C:4]([C:5]([O:7][CH2:8][CH3:9])=[O:6])=[CH:3][C:2]=2[Cl:1])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 1750274-(3-((2-(1-Hydroxycyclohexyl)ethyl)-4-oxo-2-thiazolidinyl)propyl)benzoic acidHCID 23468123Ethyl 3-chloro-4-(4-oxobutyl)benzoate

Product 1

HCID 23468102Ethyl 4-{3-[3-[2-(1-Hydroxycyclohexyl)ethyl]-4-oxo-2-thiazolidinyl]propyl}-3-chlorobenzoate

Procedure

This compound is prepared by the method described in Example 2, Step B, except that an equivalent quantity of ethyl 3-chloro-4-(4-oxobutyl)benzoate is substituted for the ethyl 4-(4-oxobutyl)benzoate of Example 2, Step B. The title compound is obtained as a viscous, brownish oil.

Workup

  1. customThis compound is prepared by the method

Sources & evidence

ORD record
ord-12fda31196224fa4b293933cc71db0fe
Source dataset
uspto-grants-1980_09
Patent number
US04225609

Linked notes

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