tert-Butanol → 1-Tert.butylamino-3-(2-methyl-4-thieno[3,2-c]pyridinyloxy)-2-propanol

Reaction equation

[C:23]([OH:24])([CH3:25])([CH3:26])[CH3:27].[C:2]([CH3:3])([CH3:4])([CH3:5])[NH:6][CH2:7][CH:8]([CH2:9][OH:10])[OH:11].[Cl:12][c:13]1[n:14][cH:15][cH:16][c:17]2[c:18]1[cH:19][c:20]([CH3:22])[s:21]2.[K:1]>>[C:2]([CH3:3])([CH3:4])([CH3:5])[NH:6][CH2:7][CH:8]([CH2:9][O:10][c:13]1[n:14][cH:15][cH:16][c:17]2[c:18]1[cH:19][c:20]([CH3:22])[s:21]2)[OH:11]

Participants

Reactant 4

HCID 6386tert-Butanol

HCID 908313-Tert-butylamino-1,2-propanediol

HCID 5462222Potassium

HCID 181763724-Chloro-2-methylthieno[3,2-c]pyridine

Product 1

HCID 214903061-Tert.butylamino-3-(2-methyl-4-thieno[3,2-c]pyridinyloxy)-2-propanol

Sources & evidence

ORD record: ord-3651a3cbdaae4897b4f8ecde9bb0e688
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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