Bicarbonate Ion → 5-(Chloromethyl)-2-phenylpyrimidine

Reaction equation

[C:19](=[O:20])([O-:21])[OH:22].[Cl:24][CH2:25][Cl:26].[Na+:23].[S:15]([Cl:16])([Cl:17])=[O:18].[c:1]1(-[c:7]2[n:8][cH:9][c:10]([CH2:13][OH:14])[cH:11][n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][cH:9][c:10]([CH2:13][Cl:17])[cH:11][n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

Reactant 5

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 21298145(2-Phenylpyrimidin-5-yl)methanol

Product 1

HCID 242297265-(Chloromethyl)-2-phenylpyrimidine

Sources & evidence

ORD record: ord-46746762a9a047f7abdef70fadc1931b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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