Water → HCID 178418235, compound

HRID 2846

Reaction equation

HRID 2846 reaction equation
[C:1]([O:7][CH2:8][CH:9]([CH3:11])[CH3:10])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].O.[Cl-].[C:14]1([N+:20]#[N:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)C>[C:14]1([NH:20][N:21]=[C:2]([C:3](=[O:4])[CH3:5])[C:1]([O:7][CH2:8][CH:9]([CH3:11])[CH3:10])=[O:6])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

5

Reactant 3

HCID 962WaterHCID 60992Benzenediazonium chlorideHCID 522677Isobutyl acetoacetate

Product 1

HCID 178418235HCID 178418235, compoundYield 88.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

15.8 g (0.1 mol) of i-butyl acetoacetate, 12 g (0.146 mol) of CH3 COONa, 20 ml of water, 75 ml of ethanol and a solution of 0.1 mol of phenyldiazonium chloride were treated as described in preparation 2. The precipitated solid was filtered an dried in vacuo yielding 23.1 g of the title compound. M.p.=45°-50° C.

Workup

  1. customas described in preparation 2
  2. filtrationThe precipitated solid was filtered
  3. customan dried in vacuo

Sources & evidence

ORD record
ord-eb91f88045c44fa2ba05b793165e13a8
Source dataset
uspto-grants-1998_03
Patent number
US05731322

Linked notes

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