Acetate → 5-(2,2-Difluoro-ethoxy)-7-chloro-2-(4-chloro-benzyl)-2,3-dihydro-isoindol-1-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([c:9]([Cl:11])[cH:10]1)[C:7](=[O:12])[N:6]([CH2:13][c:14]1[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]1)[CH2:5]2.[C:21](=[O:22])([O-:23])[O-:24].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[Cs+:25].[Cs+:26].[F:27][CH:28]([CH2:29][OH:30])[F:31].[O-:40][C:41]([CH3:42])=[O:43].[O-:44][C:45]([CH3:46])=[O:47].[Pd+2:39]>>[c:2]1([O:30][CH2:29][CH:28]([F:27])[F:31])[cH:3][c:4]2[c:8]([c:9]([Cl:11])[cH:10]1)[C:7](=[O:12])[N:6]([CH2:13][c:14]1[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]1)[CH2:5]2
