Methyl(2-(pyrrolidin-1-yl)ethyl)amine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[methyl-(2-pyrrolidin-1-yl-ethyl)amino]-thiazol-4-one

HRID 285017

Reaction equation

HRID 285017 reaction equation
[CH3:31][NH:32][CH2:33][CH2:34][N:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[Cl:1][c:2]1[cH:3][c:4]([C:27]([F:28])([F:29])[F:30])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:24])[NH:19][CH:20]([S:22][CH3:23])[S:21]4)[cH:13][cH:14][c:15]23)[cH:25][cH:26]1>>[Cl:1][c:2]1[cH:3][c:4]([C:27]([F:28])([F:29])[F:30])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:24])[N:19]=[C:20]([N:32]([CH3:31])[CH2:33][CH2:34][N:35]5[CH2:36][CH2:37][CH2:38][CH2:39]5)[S:21]4)[cH:13][cH:14][c:15]23)[cH:25][cH:26]1

Participants

3

Reactant 2

HCID 295976Methyl(2-(pyrrolidin-1-yl)ethyl)amineHCID 866565225-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one

Product 1

HCID 673456005-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[methyl-(2-pyrrolidin-1-yl-ethyl)amino]-thiazol-4-one

Sources & evidence

ORD record
ord-d8e9e60b514247cb9ea23c100c84f163
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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