HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazol-6-amine → 6-chloro-N*4*-(1H-indazol-6-yl)-pyrimidine-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazol-6-amine | HCID 81423 | — |
| Reactant | 6-chloro-4-N-(4-chlorophenyl)pyrimidine-2,4-diamine | HCID 1484285 | — |
| Product | 6-chloro-N*4*-(1H-indazol-6-yl)-pyrimidine-2,4-diamine | HCID 86004312 | 42% |
Reaction Steps
Using 1H-indazol-6-yl-amine in place of 4-chloro-phenylamine in the method described in Example 2 for the synthesis of 6-chloro-N*4*-(4-chloro-phenyl)-pyrimidine-2,4-diamine provided 6-chloro-N*4*-(1H-indazol-6-yl)-pyrimidine-2,4-diamine (42% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419984B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-9291d5801b7548cbaa3c9701328ebf7b |
| Source note | uspto-grants-2008_09 |