1H-Indazol-6-amine → HCID 11152312, compound

Participants

Reaction Steps

Following the method described in Example 26, 4-chloro-6-(5-chloro-2-methyl-phenyl)-pyrimidin-2-yl-amine and 1H-indazol-6-yl-amine provided the title compound (73% yield). 1H NMR (DMSO-d6) δ 2.37 (s, 3H, CH3), 6.17 (s, 1H, Ar), 6.35 (s, 2H, NH2), 7.30-7.33 (m, 2H, Ar), 7.37 (dd, 1H, J=8.2 Hz, J=2.3 Hz, Ar), 7.43 (d, 1H, J=2.3 Hz, Ar), 7.64 (d, 1H, J=8.6 Hz, Ar), 7.95 (s, 1H, Ar), 8.04 (s, 1H, Ar), 9.33 (s, 1H, NH), 12.80 (s, 1H, Ar).

Provenance & Evidence