3-(Chloromethyl)-5-(thiophen-2-yl)-1,2,4-oxadiazole → 1-{[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 286929

Reaction equation

HRID 286929 reaction equation
[Cl:16][CH2:17][c:18]1[n:19][o:20][c:21](-[c:23]2[s:24][cH:25][cH:26][cH:27]2)[n:22]1.[F:1][C:2]([c:3]1[c:4]2[cH:5][cH:6][nH:7][c:8]2[cH:9][cH:10][c:11]1[C:12]#[N:13])([F:14])[F:15]>>[F:1][C:2]([c:3]1[c:4]2[cH:5][cH:6][n:7]([CH2:17][c:18]3[n:19][o:20][c:21](-[c:23]4[s:24][cH:25][cH:26][cH:27]4)[n:22]3)[c:8]2[cH:9][cH:10][c:11]1[C:12]#[N:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 27983433-(Chloromethyl)-5-(thiophen-2-yl)-1,2,4-oxadiazoleHCID 674054494-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 249844551-{[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-38591ca8f8ac4e2e8eb36beb2f0955df
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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