2-Bromopropionic acid → 2-[2-(4-Cyclopropyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-propionic acid

HRID 287137

Reaction equation

HRID 287137 reaction equation
[Br:21][CH:22]([C:23](=[O:24])[OH:25])[CH3:26].[CH:1]1([c:4]2[cH:5][cH:6][c:7]([N:10]3[C:11](=[O:20])[C:12]4([CH2:13][CH2:14]3)[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]4)[cH:8][cH:9]2)[CH2:2][CH2:3]1>>[CH:1]1([c:4]2[cH:5][cH:6][c:7]([N:10]3[C:11](=[O:20])[C:12]4([CH2:13][CH2:14]3)[CH2:15][CH2:16][N:17]([CH:22]([C:23](=[O:24])[OH:25])[CH3:26])[CH2:18][CH2:19]4)[cH:8][cH:9]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 117292-Bromopropionic acidHCID 582872772-(4-Cyclopropyl-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

Product 1

HCID 582872642-[2-(4-Cyclopropyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-propionic acid

Sources & evidence

ORD record
ord-e3a3c5059bfc435489698eeb8ee19269
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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