1-Cyclopropyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethan-1-amine → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [1-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

HRID 287241

Reaction equation

HRID 287241 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[CH:21]1([C:24]([NH2:25])([c:26]2[n:27][o:28][c:29]([CH3:31])[n:30]2)[CH3:32])[CH2:22][CH2:23]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:25][C:24]([CH:21]3[CH2:22][CH2:23]3)([c:26]3[n:27][o:28][c:29]([CH3:31])[n:30]3)[CH3:32])[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 435592231-Cyclopropyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethan-1-amineHCID 710872926-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid

Product 1

HCID 710935976-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [1-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

Sources & evidence

ORD record
ord-ffe3ded7792b462e8cf4f21790b8f42f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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