5-(3-Bromo-4-fluorophenyl)-3-(2,4-difluorophenyl)-[1,2,4]triazine → 3,2'-Difluoro-5'-[3-(2,4-difluorophenyl)-[1,2,4]triazin-5-yl]biphenyl-2-carbonitrile

HRID 288008

Reaction equation

HRID 288008 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11](-[c:15]3[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]3)[n:12][n:13][cH:14]2)[cH:5][cH:6][c:7]1[F:8].[F:23][c:24]1[cH:25][cH:26][cH:27][c:28]([B:32]2[O:33][C:34]([CH3:35])([CH3:36])[C:37]([CH3:38])([CH3:39])[O:40]2)[c:29]1[C:30]#[N:31]>>[c:2]1(-[c:28]2[cH:27][cH:26][cH:25][c:24]([F:23])[c:29]2[C:30]#[N:31])[cH:3][c:4](-[c:9]2[n:10][c:11](-[c:15]3[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]3)[n:12][n:13][cH:14]2)[cH:5][cH:6][c:7]1[F:8]

Participants

3

Reactant 2

HCID 103842555-(3-Bromo-4-fluorophenyl)-3-(2,4-difluorophenyl)-[1,2,4]triazineHCID 222736032-Cyano-3-fluorophenylboronic acid pinacol ester

Product 1

HCID 100927213,2'-Difluoro-5'-[3-(2,4-difluorophenyl)-[1,2,4]triazin-5-yl]biphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-906de8f23df24221b94d3ff07db4209c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…