Benzyl 1,4-diazepane-1-carboxylate → 4-(3-Fluoro-6-methoxy-[1,5]naphthyridin-4-yl)-[1,4]diazepane-1-carboxylic acid benzyl ester

HRID 288341

Reaction equation

HRID 288341 reaction equation
[Br:18][c:19]1[c:20]([F:31])[cH:21][n:22][c:23]2[cH:24][cH:25][c:26]([O:29][CH3:30])[n:27][c:28]12.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16][CH2:17]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][N:14]([c:19]2[c:20]([F:31])[cH:21][n:22][c:23]3[cH:24][cH:25][c:26]([O:29][CH3:30])[n:27][c:28]23)[CH2:15][CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 4384955Benzyl 1,4-diazepane-1-carboxylateHCID 454803208-Bromo-7-fluoro-2-methoxy-1,5-naphthyridine

Product 1

HCID 669536944-(3-Fluoro-6-methoxy-[1,5]naphthyridin-4-yl)-[1,4]diazepane-1-carboxylic acid benzyl ester

Sources & evidence

ORD record
ord-cf831877fe1f40a2b905a61a823b417f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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