2-(6-Amino-3,4-dihydroisoquinolin-2(1H)-yl)acetamide → 2-{6-[7-(6-Methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino]-3,4-dihydro-1H-isoquinolin-2-yl}-acetamide

HRID 290194

Reaction equation

HRID 290194 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([OH:18])[n:16][n:17]23)[cH:7][n:8]1.[NH2:19][c:20]1[cH:21][c:22]2[c:27]([cH:28][cH:29]1)[CH2:26][N:25]([CH2:30][C:31](=[O:32])[NH2:33])[CH2:24][CH2:23]2>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([NH:19][c:20]4[cH:21][c:22]5[c:27]([cH:28][cH:29]4)[CH2:26][N:25]([CH2:30][C:31](=[O:32])[NH2:33])[CH2:24][CH2:23]5)[n:16][n:17]23)[cH:7][n:8]1

Participants

3

Reactant 2

HCID 574160652-(6-Amino-3,4-dihydroisoquinolin-2(1H)-yl)acetamideHCID 178488500HCID 178488500, compound

Product 1

HCID 667122542-{6-[7-(6-Methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino]-3,4-dihydro-1H-isoquinolin-2-yl}-acetamide

Sources & evidence

ORD record
ord-e31b1c77273e4a6b9a3bc122c2c8b44e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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