1-Boc-3-hydroxypiperidine → 1-(tert-Butoxycarbonyl)-3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine

HRID 291754

Reaction equation

HRID 291754 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:14])[CH2:11][CH2:12][CH2:13]1.[Cl:15][CH2:16][c:17]1[c:18]([CH3:29])[n:19][c:20](-[c:22]2[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[s:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:14][CH2:16][c:17]2[c:18]([CH3:29])[n:19][c:20](-[c:22]3[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]3)[s:21]2)[CH2:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 5456991-Boc-3-hydroxypiperidineHCID 27636945-(Chloromethyl)-2-(4-chlorophenyl)-4-methyl-1,3-thiazole

Product 1

HCID 575721401-(tert-Butoxycarbonyl)-3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine

Sources & evidence

ORD record
ord-6188acaba9864017aceba2f999c99474
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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