2-Hydroxy-5-(trifluoromethoxy)benzaldehyde → 6-[4-(2-Hydroxy-5-trifluoromethoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

HRID 294274

Reaction equation

HRID 294274 reaction equation
[N:1]1([c:7]2[cH:8][c:9](=[O:13])[nH:10][cH:11][n:12]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[OH:14][c:15]1[c:16]([CH:17]=[O:18])[cH:19][c:20]([O:23][C:24]([F:25])([F:26])[F:27])[cH:21][cH:22]1>>[N:1]1([c:7]2[cH:8][c:9](=[O:13])[nH:10][cH:11][n:12]2)[CH2:2][CH2:3][N:4]([CH2:17][c:16]2[c:15]([OH:14])[cH:22][cH:21][c:20]([O:23][C:24]([F:25])([F:26])[F:27])[cH:19]2)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 12680582-Hydroxy-5-(trifluoromethoxy)benzaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one

Product 1

HCID 1358794456-[4-(2-Hydroxy-5-trifluoromethoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

Sources & evidence

ORD record
ord-10ecb36a08194299b7ef57c0302e97aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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