HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethylbenzene-1-sulfonyl chloride → N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-ethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethylbenzene-1-sulfonyl chloride | HCID 570959 | — |
| Reactant | (2-Amino-5-bromophenyl)(pyridin-4-yl)methanone | HCID 13549724 | — |
| Product | N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-ethyl-benzenesulfonamide | HCID 10366214 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-Amino-5-bromo-phenyl)-pyridin-4-yl-methanone and 102 mg of 4-ethyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.19 (t, 3H, J=7.6 Hz), 2.62 (q, 2H, J=7.6 Hz), 7.20 (d, 2H, J=8.8 Hz, 7.38 (m, 3H), 7.65-7.72 (m, 4H), 8.81 (d, 2H, 6.4 Hz), 10.06 (s,1H). MS: m/z 446.0 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420055B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-553310262acb435cbe0610d6465d0532 |
| Source note | uspto-grants-2008_09 |