2-Chloropyridine-4-boronic acid, pinacol ester → N-(5-(2-chloropyridin-4-yl)thiazolo[5,4-b]pyridin-2-yl)-4-(2-hydroxypropan-2-yl)benzamide

HRID 295920

Reaction equation

HRID 295920 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[s:8][c:9]([NH:11][C:12]([c:13]1[cH:14][cH:15][c:16]([C:19]([CH3:20])([CH3:21])[OH:22])[cH:17][cH:18]1)=[O:23])[n:10]2.[Cl:24][c:25]1[n:26][cH:27][cH:28][c:29]([B:31]2[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]2)[cH:30]1>>[c:2]1(-[c:29]2[cH:28][cH:27][n:26][c:25]([Cl:24])[cH:30]2)[cH:3][cH:4][c:5]2[c:6]([n:7]1)[s:8][c:9]([NH:11][C:12]([c:13]1[cH:14][cH:15][c:16]([C:19]([CH3:20])([CH3:21])[OH:22])[cH:17][cH:18]1)=[O:23])[n:10]2

Participants

3

Reactant 2

HCID 51034082-Chloropyridine-4-boronic acid, pinacol esterHCID 58015365HCID 58015365, compound

Product 1

HCID 44548455N-(5-(2-chloropyridin-4-yl)thiazolo[5,4-b]pyridin-2-yl)-4-(2-hydroxypropan-2-yl)benzamide

Sources & evidence

ORD record
ord-e9cf5aabf97f4d14b10e7f24e6e6e2c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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