2-(2-Bromoethyl)-1,3-dioxolane → 4-[1-(2-[1,3]dioxolan-2-yl-ethyl)-6-fluoro-1H-indol-3-yl]-piperidine-1-carboxylic acid ethyl ester

HRID 296034

Reaction equation

HRID 296034 reaction equation
[Br:22][CH2:23][CH2:24][CH:25]1[O:26][CH2:27][CH2:28][O:29]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][nH:14][c:15]3[cH:16][c:17]([F:21])[cH:18][cH:19][c:20]23)[CH2:10][CH2:11]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][n:14]([CH2:23][CH2:24][CH:25]3[O:26][CH2:27][CH2:28][O:29]3)[c:15]3[cH:16][c:17]([F:21])[cH:18][cH:19][c:20]23)[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 877762-(2-Bromoethyl)-1,3-dioxolaneHCID 113237384-(6-fluoro-1H-indol-3-yl)-piperidine-1-carboxylic acid ethyl ester

Product 1

HCID 694118344-[1-(2-[1,3]dioxolan-2-yl-ethyl)-6-fluoro-1H-indol-3-yl]-piperidine-1-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-9102fa1232a943a8a352a73f6ddb5525
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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