7-[2-(toluene-4-sulfonyloxy)ethyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester → 7-{2-[4-(5-Chloro-pyridin-2-ylmethoxy)-6-oxo-6H-pyridazin-1-yl]-ethyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
Reaction equation
[C:43]([CH3:44])([CH3:45])([CH3:46])[O:47][C:48](=[O:49])[N:50]1[CH2:51][c:52]2[cH:53][c:54]([CH2:60][CH2:61][O:62][S:63]([c:64]3[cH:65][cH:66][c:67]([CH3:68])[cH:69][cH:70]3)(=[O:71])=[O:72])[cH:55][cH:56][c:57]2[CH2:58][CH2:59]1.[CH2:1]([O:2][c:3]1[cH:4][cH:5][n:6]([CH2:7][C:8]([c:9]2[cH:10][cH:11][c:12]([CH2:13][OH:14])[cH:15][cH:16]2)=[O:17])[c:18](=[O:19])[cH:20]1)[c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[Cl:27][c:28]1[cH:29][cH:30][c:31]([CH2:34][O:35][c:36]2[cH:37][c:38](=[O:42])[nH:39][n:40][cH:41]2)[n:32][cH:33]1>>[Cl:27][c:28]1[cH:29][cH:30][c:31]([CH2:34][O:35][c:36]2[cH:37][c:38](=[O:42])[n:39]([CH2:61][CH2:60][c:54]3[cH:53][c:52]4[c:57]([cH:56][cH:55]3)[CH2:58][CH2:59][N:50]([C:48]([O:47][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:49])[CH2:51]4)[n:40][cH:41]2)[n:32][cH:33]1Participants
4
